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We have extensive in house synthetic and manufacturing capabilities.
- Milligram and Metric Ton quantities
- Synthesis of low boiling compounds
- MT synthesis in liquid ammonia
- High pressure hydrogenation
- Acetylene compounds
- Small molecule biologics (e.g. non-natural amino acids, fluorinated amino acids)
- Low temperature reactions (-90°C)
- Organometallic reactions (grignards, alkyl lithiums, etc)
- Chiral compounds by asymmetric synthesis (either chiral auxiliaries or catalysts)
- Green reactions (ionic liquids/fluorous chemistry)
- Ketene/diketene synthesis
- Dry Box | Glove Box
Analytical Capabilities
- LC (DAD and VWD)
- MS
- GC (FID and TCD)
- GC-MS (Agilent 7890A and 7675)
- Multinuclear NMR
- CZE
- FTIR (Bruker ATR)
- UV
- Coulometric KF
- Optical Rotation
- M.P.
Process Equipment
- 1x25 gal High pressure Autocalave Reactor (1000psi 216 stainless steel)
- 2x5 gal High pressure Autoclave Reactor (2000psi 316 stainless steel)
- Glass Lined Reactors to 2000gal
- 2x55gal
- 1x25gal
- 1x150gal
- 1x750gal
- 1x1000gal
- 1x2000gal
- Stainless Reactors to 1000gal
- 1x50gal
- 2x200gal
- 1x300gal
- 2x850gal
- 2x1000gal
- 1x1000gal solid/liquid extractor
- Pilot Plant Glass Reactors:
- 10x72L
- 10x50L
- 1x100L
- Various smaller glassware down to micro-scale
- Purification/Distillation
- Packed columns (saddles, raschig rings, pro-pack) to 25’ (8”diameter)
- Spinning-band distillation
- Wiped-film distillation
- Drying
- Double cone dryer (Stainless steam jacketed)
- Tray Dryer
- Utilities/Infrastructure
- High pressure steam to 150psi
- Hot oil system to 350degC
- Glycol Chiller to -20degC
- Liquid Nitrogen (3000gal) inertion and cryogenics
- Cooling tower water
- Deionized water system
- Allen-Bradley PLC Automation on bulk reactor systems
- Ingersoll-Rand Compressed air system (15hp)
- IR Air dryer and purification system
- Laboratory Fume hoods (11) up to 12’ tall and 12’ wide
- Vacuum plant system
- Bulk Storage
- 2x10,000gal (stainless steel)
- 3x2,500gal
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